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Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Bronchiolitis

Juan Manuel Lozano1

  • 1Department of Paediatrics and Clinical Epidemiology Unit, School of Medicine, Javeriana University, Bogotá, DC, Colombia.

BMJ Clinical Evidence
|May 20, 2009
PubMed

Insights

This systematic review examines interventions for bronchiolitis, a common infant respiratory infection. It evaluates prophylactic measures, hospital transmission prevention, and various treatments for affected children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Bronchiolitis is the most frequent lower respiratory tract infection in infants, exhibiting seasonal incidence.
  • It is a primary cause for pediatric hospitalizations and emergency department visits.

Purpose of the Study:

  • To systematically review the effectiveness and safety of prophylactic interventions for high-risk children with bronchiolitis.
  • To assess measures for preventing bronchiolitis transmission within hospital settings.
  • To evaluate the efficacy of various treatments for infants diagnosed with bronchiolitis.

Main Methods:

  • A systematic review was conducted, searching major medical databases up to October 2006.
  • Included studies comprised systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • Harms alerts from regulatory agencies were also incorporated.

Main Results:

  • Forty systematic reviews, RCTs, or observational studies met the inclusion criteria.
  • The review analyzed data on a wide range of interventions.

Conclusions:

  • The systematic review provides information on the effectiveness and safety of numerous interventions.
  • Interventions evaluated include bronchodilators, chest physiotherapy, corticosteroids, nursing interventions, and specific medications like palivizumab.
Abstract

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