Related Experiment Video

Updated: Jun 23, 2026

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay

Published on: January 26, 2019

Measles, mumps, and rubella: prevention

David Elliman1, Nitu Sengupta, Haitham El Bashir

  • 1Islington PCT and Great Ormond Street Hospital, London, UK.

BMJ Clinical Evidence
|May 21, 2009
PubMed
Abstract

Insights

Measles, mumps, and rubella (MMR) vaccination significantly reduces infection risks and complications. This review evaluates the effectiveness and safety of MMR and monovalent vaccines, highlighting the importance of vaccination programs.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Vaccinology

Background:

  • Measles, mumps, and rubella cause millions of infections and deaths globally.
  • These diseases pose risks of severe complications, including neurological issues, infertility, and congenital abnormalities.
  • Decreased vaccination rates correlate with increased disease incidence.

Purpose of the Study:

  • To systematically review the effects of measles, mumps, and rubella vaccination.
  • To evaluate the effectiveness and safety of MMR and monovalent vaccines.

Main Methods:

  • Systematic review of 94 studies including systematic reviews, RCTs, and observational studies.
  • Searched major databases (Medline, Embase, Cochrane Library) up to July 2006.
  • Included harms alerts from regulatory agencies like the FDA and MHRA.

Main Results:

  • Identified 94 relevant studies meeting inclusion criteria.
  • Performed GRADE evaluation to assess the quality of evidence for interventions.

Conclusions:

  • Presents information on the effectiveness and safety of measles, mumps, and rubella vaccines.
  • Supports the use of vaccination programs to control these infectious diseases.

More Related Videos

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Related Concept Videos

Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Vaccinations01:51

Vaccinations

Overview
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...