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Disorders of the Female Reproductive System

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Updated: Jun 23, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

Breast pain.

Nigel J Bundred1

  • 1University of Manchester Department of Surgery, South Manchester University Hospital, Manchester, UK.

BMJ Clinical Evidence
|May 21, 2009
PubMed
Summary

This systematic review examines treatments for cyclical and non-cyclical breast pain, finding various interventions like diet, medication, and supplements are discussed for effectiveness and safety.

Area of Science:

  • Women's health
  • Clinical evidence synthesis
  • Pain management

Background:

  • Breast pain affects 70% of women, presenting as cyclical or non-cyclical types.
  • Cyclical breast pain often recurs, while non-cyclical pain responds poorly to treatment.
  • Understanding treatment effects is crucial for managing this common condition.

Purpose of the Study:

  • To systematically review the effects of various treatments for breast pain.
  • To evaluate the effectiveness and safety of interventions for cyclical and non-cyclical breast pain.

Main Methods:

  • Conducted a systematic review of literature up to January 2006.
  • Searched major databases including Medline, Embase, and The Cochrane Library.
  • Included harms alerts from regulatory agencies like the FDA and MHRA.

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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

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Published on: January 18, 2018

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Main Results:

  • Included 22 systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • Performed a GRADE evaluation to assess the quality of evidence for interventions.
  • Identified numerous interventions for review.

Conclusions:

  • Presents information on the effectiveness and safety of diverse breast pain treatments.
  • Interventions reviewed include dietary changes, antibiotics, hormonal therapies, and supplements.
  • Provides a comprehensive overview for clinicians managing breast pain.