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Related Concept Videos

Methods of reducing fever01:22

Methods of reducing fever

1.5K
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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Increased Body Temperature01:25

Increased Body Temperature

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
460
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

1.7K
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
1.7K
Disorder of Water Balance01:29

Disorder of Water Balance

2.8K
Water balance disorders are medical conditions that occur when there is a deviation from the body's water volume or osmolarity, disrupting normal homeostasis and leading todehydration, hypotonic hydration, hyperhydration, edema, or water intoxication.
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
2.8K
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

327
Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
327

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An evaluation of rectal artesunate for the pre-hospital management of severe malaria.

Expert opinion on pharmacotherapy·2020
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Malaria: severe, life-threatening.

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Related Experiment Video

Updated: Mar 24, 2026

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
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A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

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Malaria: fluid therapy in severe disease.

Susanne Helena Hodgson1, Brian John Angus

  • 1University of Oxford, Oxford, UK.

BMJ Clinical Evidence
|March 2, 2016
PubMed
Summary

Fluid resuscitation in severe malaria is complex. This systematic overview categorizes interventions like albumin, intravenous fluids, and blood products to guide optimal patient care and improve outcomes in this critical condition.

Area of Science:

  • Medical Research
  • Clinical Medicine
  • Parasitology

Background:

  • Severe malaria disproportionately affects vulnerable populations, including young children and non-immune individuals.
  • Cerebral malaria presents a high mortality rate (around 20%) and can cause long-term neurological damage in survivors.
  • Severe malarial anemia also carries a significant mortality risk exceeding 13%.

Purpose of the Study:

  • To determine the optimal method of fluid resuscitation for patients diagnosed with severe malaria.
  • To systematically review existing evidence on fluid management strategies in severe malaria.

Main Methods:

  • A systematic overview was conducted, searching major medical databases up to December 2014.
  • The review included screening 93 records, with 11 full publications undergoing detailed evaluation.

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Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding

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High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
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High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays

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Last Updated: Mar 24, 2026

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
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Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding
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High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
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  • GRADE methodology was applied to assess seven PICO (Population, Intervention, Comparison, Outcome) combinations.

    • Main Results:

    • The search identified 187 studies, which were refined to 11 full articles for analysis.
    • Two systematic reviews and three randomized controlled trials (RCTs) were newly incorporated in this update.
    • A GRADE evaluation was performed for seven specific PICO scenarios.

    Conclusions:

    • The study categorized the efficacy of three key interventions: human albumin, intravenous fluids, and whole blood or plasma.
    • This categorization aims to inform clinical decision-making regarding fluid resuscitation in severe malaria.
    • The findings provide a basis for understanding the effectiveness and safety of different fluid management approaches.