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Updated: Jun 23, 2026

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Summary
Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) treatments were reviewed. This systematic review evaluated interventions like CPAP, oral appliances, and weight loss for OSAHS effectiveness and safety.
Area of Science:
- Sleep Medicine
- Respiratory Medicine
- Public Health
Background:
- Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) is a common condition affecting up to 24% of men and 9% of women in the US.
- Obesity is a significant risk factor for OSAHS.
- OSAHS is characterized by upper airway obstruction during sleep.
Purpose of the Study:
- To systematically review the effects of treatments for severe OSAHS.
- To systematically review the effects of treatments for non-severe OSAHS.
Main Methods:
- Systematic review of scientific literature up to May 2006.
- Searched Medline, Embase, and The Cochrane Library.
- Included harms alerts from FDA and MHRA.
Main Results:
- Included 25 systematic reviews, RCTs, or observational studies.
- Evaluated the quality of evidence using the GRADE system.
- Presented information on intervention effectiveness and safety.
Conclusions:
- Effectiveness and safety data were compiled for various OSAHS interventions.
- Interventions reviewed include compliance measures, nasal CPAP, oral appliances, and weight loss.
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