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Updated: Jun 23, 2026
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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
Published on: July 28, 2020
Long-term results after resection for soft tissue sarcoma pulmonary metastases
Carlos E García Franco1, Salvador Martín Algarra, Akiko Tamura Ezcurra
1Department of General Thoracic Surgery, Clinica Universidad Navarra, Avenida Pio XII 36, Pamplona 31008, Spain. cegarciaf@unav.es
Interactive Cardiovascular and Thoracic Surgery
|May 21, 2009
Summary
Prognostic factors for soft tissue sarcoma (STS) pulmonary metastases include disease-free interval, number of lung nodules, and histology. These factors impact long-term survival rates for patients undergoing surgical resection.
Area of Science:
- Oncology
- Surgical Oncology
- Medical Oncology
Background:
- Pulmonary metastases from soft tissue sarcomas (STS) affect approximately 20% of patients.
- Current standard treatments include chemotherapy and surgical resection.
Purpose of the Study:
- To identify prognostic factors for patients with pulmonary metastases from STS.
- To estimate the long-term survival rates in this patient cohort.
Main Methods:
- Retrospective analysis of 22 consecutive patients treated between 1996 and 2006.
- Univariate analysis (log-rank, Cox-regression) for prognostic factor identification.
- Kaplan-Meier methods for estimating five-year survival rates.
Main Results:
- Median follow-up was 14 months, with a median survival of 19 months.
- Significant prognostic factors identified: disease-free interval (DFI), number of lung nodules, and histology type.
- Overall five-year survival rate was 23.1%.
Conclusions:
- Disease-free interval, number of lung nodules at surgery, and metastatic histology are significant prognostic indicators.
- These factors are crucial for managing patients with resected pulmonary metastases from STS.
