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[Effectiveness and tolerance of aerosol disodium cromoglycate in children with bronchial asthma]

J Zarkovic1, R Angermayr, B Covi

  • 1Universitäts-Kinderklinik, Wien.

Padiatrie Und Padologie
|January 1, 1991
PubMed

Insights

Nebulized cromolyn solution effectively reduced asthma symptoms in children. This asthma treatment showed significant improvement and no side effects during the study.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology

Background:

  • Childhood asthma presents a significant health burden.
  • Current asthma management often involves multiple medications.

Purpose of the Study:

  • To evaluate the efficacy and safety of nebulized cromolyn solution for pediatric asthma.
  • To assess the impact on daily asthma symptoms and medication use.

Main Methods:

  • A multi-center study involving 53 children with asthma.
  • Treatment with nebulized cromolyn solution over a five-week period.
  • Daily symptom scoring by investigators and parents.

Main Results:

  • Significant reduction in investigator-assessed asthma symptoms.
  • Significant improvement in parent-assessed daily symptom scores.
  • Marked decrease in the use of adjunctive asthma medications (beta 2-sympathomimetics, theophylline, antihistamines).

Conclusions:

  • Nebulized cromolyn solution is an effective treatment for childhood asthma.
  • The treatment demonstrated a favorable safety profile with no reported side effects.
  • Nebulized cromolyn solution may reduce the need for other asthma medications.

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