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The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

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Published on: June 30, 2014

Sweating impairment in patients with multiple sclerosis.

A Saari¹, U Tolonen, E Pääkkö

¹Department of Neurology, Oulu University Hospital, Oulu, Finland. anne.saari@ppshp.fi

Acta Neurologica Scandinavica

|May 22, 2009

Summary

This summary is machine-generated.

Patients with multiple sclerosis (MS) exhibit significantly reduced thermoregulatory sweating compared to healthy individuals. This impairment in sweating appears to correlate with the severity of MS disease.

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Quantitative Autonomic Testing

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Published on: July 19, 2011

Area of Science:

Neurology
Physiology

Background:

Multiple sclerosis (MS) is a chronic neurological disease.
Thermoregulation is a critical bodily function that can be affected in MS.

Purpose of the Study:

To quantify and compare sweating responses between individuals with MS and healthy controls.
To investigate the relationship between MS disease severity and sweating capacity.

Main Methods:

Sweating was measured using an evaporimeter following a controlled heating stimulus.
The study included 29 patients diagnosed with multiple sclerosis and 15 healthy control subjects.

Main Results:

Multiple sclerosis patients demonstrated significantly reduced sweating across various body areas, including the forehead, feet, and legs, after 10 minutes of heating.
This difference remained statistically significant in the feet after 15 minutes of heating.
A negative correlation was observed between the Expanded Disability Status Scale score and sweating levels, particularly in the hands and feet, indicating greater impairment with increased disease severity.

Conclusions:

Multiple sclerosis is associated with impaired thermoregulatory sweating.
The degree of sweating impairment in MS patients appears to be linked to the overall severity of the disease.