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Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
[Eradication of hepatitis C virus after a 5-week treatment]
G L Gaundong Mbéthé1, J Foucher, V DeLedinghen
1Service d'hépatogastro-entérologie, hôpital Haut-Lévêque, CHU de Bordeaux, Pessac cedex, France. gaundong@yahoo.fr
Abstract:
The standard regimen for the treatment of chronic hepatitis C virus (HCV) is peginterferon alpha-2a or -2b associated with ribavirine. The recommended duration of treatment for genotype 2 HCV infection is 24 weeks. However, the relatively poor drug tolerance often leads to a reduction or a discontinuation of the treatment. Here, we report two female patients who discontinued antiviral therapy after less than 6 weeks for intolerance and who experienced a sustained virological response. A treatment of 3 to 5 weeks may be enough for genotype 2 HCV eradication. However, there is not sufficient evidence in 2009 to recommend a reduced treatment duration.
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