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Sexual quality of life is impaired in patients with chronic hepatitis C

J Vergniol1, S Duc1, G Hou2

  • 1Centre Expert Hépatites Virales Aquitaine, Service d'Hépato-Gastroentérologie, Hôpital Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, Pessac, France.

International Journal of Impotence Research
|February 12, 2016
PubMed

Insights

Chronic hepatitis C (CHC) significantly impairs sexual function in both men and women. This study highlights the need to assess and treat sexual quality of life in CHC patients.

Area of Science:

  • Hepatology
  • Sexual Medicine
  • Quality of Life Research

Background:

  • Chronic hepatitis C (CHC) is known to affect patients' quality of life.
  • Limited data exist regarding sexual impairment (SI) in CHC patients.
  • Understanding SI in CHC is crucial for comprehensive patient care.

Purpose of the Study:

  • To investigate the prevalence and factors associated with sexual impairment in adult CHC patients.
  • To compare sexual function in CHC patients with healthy controls.
  • To emphasize the importance of addressing sexual health in clinical practice for CHC.

Main Methods:

  • A cross-sectional study comparing 281 CHC outpatients (2011-2013) with 1086 healthy blood donors.
  • Utilized adapted International Index of Erectile Function and Female Sexual Function Index questionnaires.
  • Multivariate analysis and propensity score-matching were employed to identify associated factors.

Main Results:

  • Sexual impairment was significantly more frequent in CHC patients compared to controls.
  • CHC men reported worse desire, confidence, erections, climax, and satisfaction (P<0.001).
  • CHC women reported worse desire, arousal, climax, satisfaction, lubrication, and comfort (P<0.001).
  • Independent factors for SI in men included CHC, age, no intercourse, and unemployment.
  • Independent factors for SI in women included CHC and no intercourse.

Conclusions:

  • Sexual life quality is significantly impaired in both men and women with chronic hepatitis C.
  • CHC is a strong independent predictor of sexual dysfunction in both genders.
  • Clinical evaluation and treatment of sexual quality of life should be integrated into the management of CHC patients.

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