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[Inflammatory pseudotumours of spleen]
Srpski Arhiv Za Celokupno Lekarstvo
|May 23, 2009
Summary
Inflammatory pseudotumours of the spleen, though rare, are increasingly diagnosed. Splenectomy is the recommended treatment for these benign lesions.
Area of Science:
- Pathology
- Surgical Oncology
Background:
- Inflammatory pseudotumours are rare, benign splenic lesions of unknown cause.
- They often present with non-specific symptoms or are found incidentally.
- Differential diagnosis includes lymphomas and other lymphoproliferative disorders.
Observation:
- Presents three female patients (ages 36, 48, 56) with splenic inflammatory pseudotumours.
- Symptoms included mild abdominal pain; one case discovered after trauma.
- Laboratory findings were largely unremarkable, with elevated white blood cells in one patient.
Findings:
- All patients underwent splenectomy due to suspicion of splenic lymphoma.
- Histological and immunohistochemical examination confirmed the diagnosis of inflammatory pseudotumour.
- Two patients experienced transient postsplenectomy thrombocytosis, managed with aspirin.
Implications:
- Inflammatory pseudotumours of the spleen may be underdiagnosed.
- Advanced imaging (US, CT, MRI) is increasing detection rates.
- These tumours should be considered in the differential diagnosis of splenic lesions, with splenectomy as the treatment of choice.
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