Related Experiment Video
Updated: Jun 23, 2026
An Open-Source Normothermic Perfusion System Designed for Research Scientists
Published on: July 18, 2025
[Introduction of a MR-compatible system for extracorporal perfusion of vital organs for MR-guided
Gunnar Gaffke1, Stefan Nagel, Olaf Hegemann
1Universitätsklinikum Magdeburg, Klinik für Radiologie und Nuklearmedizin, Leipziger Strasse 44, 39120 Magdeburg, Germany. gunnar.gaffke@med.ovgu.de
Purpose:
To represent a MRI-compatible perfusion-system for extracorporeal perfusion of vital organs which permits the realisation of realistic experiments in a MR scanner.
Material And Methods:
We performed MR examinations of explanted porcine livers and MR-guided interventions in porcine livers. Explanted organs were hemo-perfused under physiological conditions during the experiments. MR-sequences for diagnostic and interventional examinations were used.
Results:
The evaluated system was MRI-compatible. The achieved image quality of the used sequences showed excellent anatomical resolution. Planned experiments can be carried out with relatively low expenditure. Diagnostic as well as interventional investigations can be carried out. The used organs showed a stable function within physiological parameters up to 4 hours.
Conclusion:
It is possible to perform ex vivo experiments under in vivo conditions with this system. With the used MR-compatible system MR-guided experimental interventions and thermal ablations can be carried out in explanted organs under in vivo conditions.