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Updated: Jun 23, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
[Cardiovascular disease and chronic kidney disease: from treatment to promoting health]
1The Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Cardiovascular Health Center, The Mount Sinai School of Medicine, New York, NY 10029, USA.
Insights
Screening for chronic kidney disease (CKD) is vital in patients with cardiovascular disease or risk factors like hypertension and diabetes. Early identification and prevention strategies are crucial to combat the growing global epidemic of CKD.
Area of Science:
- Nephrology
- Cardiology
- Public Health
Context:
- Chronic kidney disease (CKD) is strongly linked to adverse cardiovascular outcomes.
- Cardiovascular disease patients and those with risk factors (hypertension, diabetes) require CKD screening.
- Global rise in CKD presents significant economic challenges.
Purpose:
- To emphasize the necessity of screening for CKD in at-risk populations.
- To advocate for integrated strategies in CKD prevention and management.
- To propose expanding global health goals to include chronic diseases like CKD.
Summary:
- Screening for CKD should utilize estimated glomerular filtration rate and urine albumin-to-creatinine ratio.
- Comprehensive prevention programs must assess lifestyle factors (tobacco, diet, exercise), BMI, blood pressure, lipids, glucose, and cancer screening.
- A shift from treating renal failure to aggressive primary and secondary prevention is essential.
Impact:
- Highlights the urgent need for proactive CKD identification and management.
- Promotes a holistic approach to disease prevention, integrating CKD with other chronic conditions.
- Calls for global health initiatives to address the escalating burden of CKD and related diseases.
Abstract:
Chronic kidney disease is associated with poor cardiovascular outcomes and should be screened for in all patients with cardiovascular disease or risk factors such as hypertension and diabetes mellitus using estimate of glomerular filtration rate and a random urine albumin-to creatinine ratio. Strategies to identify and prevent chronic kidney disease must be part of a comprehensive program of disease prevention, that include evaluation of tobacco use, diet and exercise patterns, body mass index, blood pressure, lipid profile, blood glucose and patient-appropriate cancer screening. The global increase in patients with chronic kidney disease is threatening to reach epidemic proportions over the next decade, and few countries will be able to meet the economic challenges posed. A change in global approach from treatment of renal failure to aggressive primary and secondary prevention is essential. We propose that the United Nations Millennium Developments Goals for 2000-2015 should be expanded to include combatting infectious diseases as well as chronic diseases such as cardiovascular disease, diabetes, renal disease and cancer, using an integrated approach.
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