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Calculating postnatal growth velocity in very low birth weight (VLBW) premature infants

A L Patel1, J L Engstrom, P P Meier

  • 1Pediatrics, Rush University Medical Center, Chicago, IL 60612, USA. aloka_patel@rush.edu

Journal of Perinatology : Official Journal of the California Perinatal Association
|May 23, 2009
PubMed

Insights

The exponential model (EM) accurately estimates growth velocity (GV) in hospitalized very low birth weight (VLBW) infants, outperforming the 2-Point model (2-PM). This validated EM offers a consistent approach for assessing VLBW infant growth.

Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Growth Monitoring

Background:

  • Standardized growth velocity (GV) calculation is lacking for hospitalized very low birth weight (VLBW) infants.
  • Disparate GV estimation methods hinder comparability across Neonatal Intensive Care Units (NICUs) and studies.

Purpose of the Study:

  • To compare actual GV calculated from daily weights with estimated GV using the exponential model (EM) and 2-Point model (2-PM).
  • To validate mathematical models for accurate GV assessment in VLBW infants.

Main Methods:

  • Actual GV calculated from daily weights of 81 VLBW infants (1000-1499g BW) from birth and regain of birth weight (BW).
  • Comparison of actual GV with estimated GV from EM and 2-PM.

Main Results:

  • The EM demonstrated <1% mean absolute difference from actual GV for all infants.
  • The 2-PM showed <1% error for only 38% (from birth) and 44% (from regain BW) of infants.
  • EM accuracy was unaffected by decreasing BW and increasing NICU stay, unlike the 2-PM.

Conclusions:

  • The EM provides highly accurate GV estimates in VLBW infants, unaffected by common clinical factors.
  • The EM is validated for consistent and simple GV assessment in all VLBW infants.
  • The EM offers a standardized approach to growth monitoring in NICU populations.
Abstract

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