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Updated: Jun 23, 2026
05:06
Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
Published on: July 14, 2023
[Pathophysiology and treatment for diabetic neuropathy]
1Facuty of Nursing, Shiga University of Medical Science.
Rinsho Shinkeigaku = Clinical Neurology
|May 26, 2009
Summary
Diabetic neuropathy (DN) is a common complication. Effective management requires strict glycemic control, lifestyle changes, and excluding other neuropathies, with limited drug options currently available.
Area of Science:
- Neurology
- Endocrinology
- Diabetology
Context:
- Diabetic neuropathy (DN) is the most prevalent peripheral neuropathy.
- Its complex pathophysiology hinders established classification and treatment strategies.
- Sensory/autonomic polyneuropathy (DP) represents the primary form of DN.
Purpose:
- To review the current understanding and management of diabetic neuropathy.
- To highlight the challenges in diagnosing and treating DN, especially differentiating it from other neuropathies.
- To discuss preventive measures, existing treatments, and future therapeutic directions.
Summary:
- DN management necessitates ruling out other conditions like CIDP and maintaining strict glycemic control (HbA1c < 6.5%).
- Lifestyle modifications, including restricting alcohol/smoking and managing blood pressure, are crucial for retarding DN progression.
- Aldose reductase inhibitors are the sole approved drug, requiring evaluation via nerve function tests and symptom assessment.
Impact:
- Emphasizes the need for comprehensive diagnostic approaches to DN.
- Underscores the importance of integrated management involving glycemic control and lifestyle adjustments.
- Highlights the demand for novel therapeutic agents targeting DN's underlying mechanisms, including gene-based therapies.
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