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Postviral vagal neuropathy.

Catherine J Rees1, Arthur H Henderson, Peter C Belafsky

  • 1Center for Voice and Swallowing Disorders, Wake Forest University, Winston-Salem, North Carolina, USA.

The Annals of Otology, Rhinology, and Laryngology
|May 26, 2009
PubMed
Summary
This summary is machine-generated.

Postviral vagal neuropathy (PVVN) causes laryngeal symptoms like chronic cough and voice issues after an upper respiratory infection (URI). This study details PVVN

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Area of Science:

  • Otolaryngology
  • Neurology
  • Laryngology

Background:

  • Postviral vagal neuropathy (PVVN) presents with laryngeal complaints following an upper respiratory infection (URI).
  • Limited data exists on the natural history and clinical presentation of PVVN.
  • Previous reports primarily consist of small case series.

Purpose of the Study:

  • To describe the clinical presentation, symptoms, patient demographics, and natural history of Postviral vagal neuropathy (PVVN).
  • To characterize the typical patient profile and symptom progression in PVVN.
  • To identify common diagnostic challenges and delays in referral for PVVN patients.

Main Methods:

  • A cross-sectional survey was conducted on 44 patients diagnosed with PVVN between January 1, 2006, and December 31, 2006.
  • Data collected included disease onset, symptom type and duration, demographics, and prior treatments.
  • Validated instruments like the Reflux Symptom Index and Voice Handicap Index were used, alongside laryngoscopic findings.

Main Results:

  • The study identified 44 PVVN patients, with a mean age of 48 years, predominantly female (73%).
  • Common initial URI symptoms included cough (89%), nasal congestion (75%), and rhinorrhea (64%).
  • Persistent symptoms were chronic cough (52%), throat clearing (48%), dysphonia (41.5%), and vocal fatigue (43%), with 49% showing vocal fold paresis.

Conclusions:

  • Postviral vagal neuropathy (PVVN) is a distinct clinical entity following URIs, marked by chronic cough, throat clearing, dysphonia, and vocal fatigue.
  • Affected individuals are typically middle-aged women, often experiencing significant delays in diagnosis and referral to a laryngologist.
  • The study highlights the complex nature of PVVN and the need for increased awareness among clinicians.