Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hormonal Regulation01:33

Hormonal Regulation

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the Role of Coenzyme A Restriction in the Pathophysiology of Preeclampsia: Protocol for a Combined Patient Screening and Laboratory Study.

JMIR research protocols·2025
Same author

Prevalence and prenatal diagnosis of major congenital anomalies in Dubai: first insights and emerging patterns in a multicenter cohort study.

BMC pregnancy and childbirth·2025
Same author

Prevalence and Diagnosis of PCOS Using Electronic Health Records: A Scoping Review and a Database Analysis.

International journal of environmental research and public health·2024
Same author

Prevalence of Polycystic Ovary Syndrome amongst Females Aged between 15 and 45 Years at a Major Women's Hospital in Dubai, United Arab Emirates.

International journal of environmental research and public health·2023
Same author

Polycystic Ovarian Syndrome (PCOS): Does the Challenge End at Conception?

International journal of environmental research and public health·2022
Same author

Effect of Sustained Uterine Compression versus Uterine Massage on Blood Loss after Vaginal Delivery: A Randomized Controlled Trial.

American journal of perinatology·2021
Same journal

Congenital cytomegalovirus: Screening strategies and diagnostic challenges.

Seminars in perinatology·2026
Same journal

The society for neonatal nutrition and lifelong health: Building science and translating research to inform neonatal nutritional care.

Seminars in perinatology·2026
Same journal

Enteral nutrition to optimize health and neurodevelopmental outcomes in very preterm infants.

Seminars in perinatology·2026
Same journal

Standardizing outcome measures in preterm infant nutrition research: Use of anthropometry and body composition in the neonatal intensive care unit.

Seminars in perinatology·2026
Same journal

A dilemma of parental inclusion? Parent perspectives of NICU feeding practices and neonatal nutritional research.

Seminars in perinatology·2026
Same journal

Maternal diet and nutritional status during pregnancy and lactation: a review of implications on milk composition and lactation outcomes.

Seminars in perinatology·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Pre-eclampsia and the kidney.

Fadi G Mirza1, Kirsten Lawrence Cleary

  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA. fgm2107@columbia.edu

Seminars in Perinatology
|May 26, 2009
PubMed
Summary
This summary is machine-generated.

Pre-eclampsia, a pregnancy disorder, significantly impacts kidney function, increasing risks for those with existing renal disease. Understanding these kidney changes is crucial for managing this condition.

More Related Videos

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

Related Experiment Videos

Last Updated: Jun 22, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

Area of Science:

  • Nephrology
  • Obstetrics
  • Maternal-Fetal Medicine

Background:

  • Pre-eclampsia affects at least 5% of pregnancies, characterized by new-onset hypertension and proteinuria.
  • The kidneys undergo significant physiological and pathological changes during pregnancy, making them central to pre-eclampsia.
  • There is a known interplay between renal disease and pre-eclampsia, with proteinuria being a universal diagnostic marker.

Purpose of the Study:

  • To review the physiological adaptations of the kidney during pregnancy.
  • To examine the impact of pre-eclampsia on renal function.
  • To assess the risk of pre-eclampsia in women with pre-existing chronic renal disease.

Main Methods:

  • Literature review focusing on renal physiology in pregnancy.
  • Analysis of pre-eclampsia's effects on kidney function.
  • Examination of epidemiological data regarding chronic renal disease and pre-eclampsia risk.

Main Results:

  • Pregnancy involves substantial renal physiological changes.
  • Pre-eclampsia can lead to significant renal pathology, including acute renal failure.
  • Women with underlying renal disease face a higher risk of developing pre-eclampsia and its complications.

Conclusions:

  • The kidney is a vital organ significantly affected by pre-eclampsia.
  • Pre-existing renal conditions increase the susceptibility to and severity of pre-eclampsia.
  • Pregnant women with systemic lupus erythematosus and those with a history of renal transplantation require special consideration.