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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Restorative Care01:19

Restorative Care

Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

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Related Experiment Video

Updated: Jun 22, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

[Elderly in an acute geriatric unit].

Luis Romero Rizos1, Pedro Manuel Sánchez Jurado, Pedro Abizanda Soler

  • 1Sección de Geriatría, Complejo Hospitalario Universitario de Albacete, Albacete, España.

Revista Espanola De Geriatria Y Gerontologia
|May 26, 2009
PubMed
Summary
This summary is machine-generated.

Acute geriatric units (AGUs) improve hospitalization outcomes for frail elderly patients, reducing functional loss and increasing home returns. Despite strong evidence, their implementation in Spain remains low, highlighting a critical healthcare gap.

Related Experiment Videos

Last Updated: Jun 22, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Area of Science:

  • Geriatrics
  • Hospital Medicine
  • Health Services Research

Context:

  • Acute geriatric units (AGUs) are evidence-based interventions for frail elderly patients.
  • Spain has a low implementation rate (12%) of AGUs despite strong evidence.
  • There is an estimated need for 2.6 geriatric specialized beds per 1000 inhabitants over 75 years old.

Purpose:

  • To review the characteristics of patients who benefit from AGUs.
  • To outline the services, structure, and functioning of AGUs.
  • To define the roles of healthcare professionals and essential quality indicators for AGUs.

Summary:

  • AGUs are highly effective in managing acute illness in frail older adults.
  • These units reduce hospitalization-related functional decline and improve discharge destinations.
  • AGUs do not increase mortality or healthcare costs.

Impact:

  • Highlights the underutilization of AGUs in Spain, indicating a need for increased adoption.
  • Provides a comprehensive overview for establishing and optimizing AGUs.
  • Supports the integration of specialized geriatric care into general hospitals to improve outcomes for older populations.