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Related Experiment Video

Updated: Jun 22, 2026

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

Published on: September 16, 2022

Bone creep can cause progressive vertebral deformity.

Phillip Pollintine¹, Jin Luo, Ben Offa-Jones

¹Department of Mechanical Engineering, University of Bath, Bath, UK.

|May 26, 2009

Summary

This summary is machine-generated.

Elderly vertebrae can develop progressive wedge deformities under sustained load, even without fractures. This creep deformation is linked to bone mineral density, highlighting a time-dependent process in spinal aging.

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Last Updated: Jun 22, 2026

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

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Mouse Lumbar Vertebra Uniaxial Compression Testing with Embedding of the Loading Surface

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Published on: December 1, 2023

Area of Science:

Biomechanics
Gerontology
Orthopedics

Background:

Vertebral deformities in the elderly are often termed fractures but may involve insidious, time-dependent creep processes.
Previous creep studies focused on small bone samples; whole vertebra creep and its relation to bone mineral density (BMD) were unknown.

Purpose of the Study:

To investigate if sustained compressive loading causes progressive creep deformity in elderly human vertebrae.
To determine the influence of bone mineral density (BMD) on this creep deformity.

Main Methods:

27 thoracolumbar motion segments from human cadavers (aged 42-91 yrs) were subjected to constant compressive force (approx. 1.0 kN) for 0.5 h or 2 h.
Anterior, middle, and posterior vertebral body heights were measured using optical tracking; volumetric BMD was calculated using DXA.

Main Results:

Sustained loading caused significant anterior creep deformation (averaging 4331 micro-strains) and increased anterior wedging.
Creep rate slowed over time, with limited recovery; anterior wedging increase was inversely proportional to BMD in specimens with low BMD.
Four vertebrae experienced >5% height loss, three with pre-existing damage.

Conclusions:

Sustained loading induces progressive anterior wedge deformity in elderly vertebrae, independent of fracture.
This creep phenomenon contributes to vertebral changes in aging and may be influenced by bone mineral density.