Isolated limb infusion: technique description and clinical application.

Area of Science:

• Oncology
• Interventional Radiology
• Minimally Invasive Procedures

Background:

• Regionally advanced cancers often present challenges for systemic therapy and surgical resection.
• Minimally invasive techniques are increasingly explored for complex oncological management.
• Isolated limb infusion (ILI) is a novel approach for localized cancer treatment.

Observation:

• The study reports the initial single-center experience with ILI over one year.
• Three patients with advanced peripheral melanoma and one with lower-extremity cutaneous T-cell lymphoma were treated.
• The ILI procedure was performed entirely within the interventional radiology suite.

Findings:

• The complete ILI procedure was feasible in a single session lasting 60-100 minutes.
• No patient transfer to the operating room was required.
• There was no additional waiting time between catheter insertion and chemotherapy infusion.

Implications:

• ILI demonstrates potential as an efficient, localized treatment option for specific advanced cancers.
• The technique streamlines patient care by consolidating treatment within the interventional radiology suite.
• Further research into ILI's efficacy and broader applicability in oncology is warranted.