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Updated: Jun 22, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
09:38

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Published on: January 31, 2025

Isolated limb infusion: technique description and clinical application

Carmel G Cronin1, Derek G Lohan, Conor O'Riordan

  • 1Department of Radiology, University College Hospital, Newcastle Road, Galway, Ireland. carmelcronin2000@hotmail.com

Journal of Vascular and Interventional Radiology : JVIR
|May 26, 2009
PubMed

Isolated limb infusion (ILI) is a recently described minimally invasive technique indicated in the management of regionally advanced cancers refractory to systemic therapy and surgery. The present report describes the initial single-center experience of three patients with regionally advanced peripheral melanoma and one with lower-extremity cutaneous T-cell lymphoma treated over a period of 1 year. It is feasible to perform the complete ILI procedure in a single 60-100-minute session, solely in the interventional radiology suite, without a requirement for patient transfer to the operating room or extra waiting time between catheter insertion and chemotherapy infusion treatment.

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