Related Experiment Video
Updated: Jun 22, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Endoscopic transnasal study of the infratemporal fossa: a new orientation
Islam R Herzallah1, Ross Germani, Roy R Casiano
1Department of Otolaryngology, Faculty of Medicine, Zagazig University, Egypt. iherzallah@gmail.com
Introduction:
The medial portion of the infratemporal fossa (ITF) is not infrequently involved in sinonasal and skull base pathologies. However, endoscopic view of the ITF remains unclear with lack of studies addressing this region from the endoscopic perspective.
Methods:
Using an extended endoscopic approach, the pterygopalatine and infratemporal fossae were dissected in 10 sides of five adult cadaver heads. A plane of dissection along the pterygoid base and the infratemporal surface of the greater sphenoid wing was developed. High-quality images were produced by coupling the video camera to a digital recording system.
Results:
The foramen rotundum, ovale, and spinosum were accessed and new landmarks were described from the endoscopic point of view. The sphenomandibularis muscle was also highlighted. Maxillary and mandibular nerves and middle meningeal artery were all identified. Columellar measurements to the foramen rotundum and ovale ranged from 6.1 to 8.0 cm for the former and 7.0 to 9.1 cm for the latter, with a mean of 6.75 cm and 7.78 cm respectively.
Conclusion:
The current study provides a novel endoscopic orientation to the medial ITF. Such knowledge should provide an anatomical basis for experienced surgeons to endoscopically address this region with more safety and efficacy.
