Related Experiment Video
Updated: Jun 22, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
Antimicrobial and cytotoxic activities of Malaysian endophytes
Kalavathy Ramasamy1, Siong Meng Lim, Hamidah Abu Bakar
1Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor Darul Ehsan, Malaysia. kalav922@salam.uitm.edu.my
Abstract:
Endophytes, which are receiving increasing attention, have been found to be potential sources of bioactive metabolites following the discovery of paclitaxel producing endophytic fungi. In the present study, a total of 348 endophytes were isolated from different parts of 24 Malaysian medicinal plants. Three selected endophytes (HAB10R12, HAB11R3 and HAB21F25) were investigated for their antimicrobial and cytotoxic activities. For antimicrobial activity, HAB10R12 and HAB11R3 were found to be most active against bacteria and fungi, respectively. Their antimicrobial effects were comparable to, if not better than, a number of current commercial antibacterial and antifungal agents. Both HAB10R12 and HAB21F25 were found to be potential anticancer drug candidates, having potent activity against MCF-7 and HCT116 cell lines and warrant further investigation.
Related Concept Videos
Antimicrobial Effectiveness
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Antifungal Agents
Clinical Significance of Antibiotic Resistance
Biological Methods for Microbial Control
Combined Effects of Drugs: Synergism
Such synergistic combinations...
