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In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
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In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity

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System-wide changes to SUMO modifications in response to heat shock

Filip Golebiowski1, Ivan Matic, Michael H Tatham

  • 11Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK.

Science Signaling
|May 28, 2009
PubMed
Summary

Small ubiquitin-like modifier (SUMO) proteins are crucial for cells to survive heat shock. This study reveals how SUMOylation changes across many proteins during heat stress, impacting vital cellular processes.

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