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Updated: Jun 22, 2026

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG
Published on: March 10, 2017
Regulation of DGK-theta
Becky Tu-Sekine1, Daniel M Raben
1Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. btusekine@jhmi.edu
Abstract:
Diacylglycerol kinases are important regulators of lipid signaling and, consequently, important regulators of many diglyceride-dependent and PA-dependent proteins. Research over the last twenty years has clearly demonstrated that individual DGK isoforms can be connected with disparate cellular processes, indicating the presence of a sophisticated regulatory network for diglyceride and phosphatidic acid signaling through the regulation of individual DGK isoforms. This review presents the progress on the characterization of a primarily neuronal isoform DGK-theta, and examines current data on the primary structure, regulation and potential cellular functions of this enzyme.
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