Time- and loading-dependence in the McKone model for dermal uptake of organic chemicals from a soil matrix

McKone has recently proposed an innovative two-layer model for dermal uptake of organic chemicals from a soil matrix that explicitly includes variables for properties of the chemical, the soil, the skin, and the exposure. In this note, we investigate the joint time- and loading-dependencies implicit in the model by using MATHEMATICA to find and plot a closed-form function for the uptake fraction for six aromatic hydrocarbons.