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Amanita phalloides poisoning-induced end-stage renal failure
C Garrouste1, M Hémery, A M Boudat
1Department of Nephrology, Tarbes, University Hospital, CHU Rangueil, Toulouse, France.
Abstract:
Fungi poisoning is quite frequent: in particular, Amanita phalloides has life-threatening toxicity. It is responsible for fulminant hepatitis, and also has renal toxicity. Herein, we report on a patient who developed acute renal failure after ingesting A. phalloides, which required definitive renal replacement therapy, despite rapid liver injury recovery. A kidney biopsy showed massive acute tubular necrosis, mainly in the proximal convoluted tubule, and mild interstitial infiltration by mononuclear cells.
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