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[Cutaneous epithelial necrosis in coma. Study of 2 cases]
A Hasson1, M C Gutiérrez, D Arias
1Departamento de Anatomía Patológica, Fundación Jiménez, Díaz, Madrid.
Revista Clinica Espanola
|July 1, 1991
Summary
Two comatose patients developed skin lesions including erythematous plaques and bullae. Histology revealed epidermal necrosis and characteristic eosinophilic necrosis of sweat gland coils.
Area of Science:
- Dermatology
- Pathology
Background:
- Comatose patients are susceptible to various medical complications.
- Cutaneous manifestations can indicate underlying systemic issues.
Observation:
- Two comatose patients presented with evolving skin lesions.
- Lesions initially appeared as erythematous plaques, progressing to bullous formations.
Findings:
- Histological examination confirmed epidermal necrosis and subepidermal blisters.
- A key finding was eosinophilic necrosis specifically affecting eccrine sweat gland coils.
- A sparse neutrophilic infiltrate was also noted.
Implications:
- This pattern of cutaneous necrosis may be a specific indicator in comatose patients.
- Further research is needed to understand the etiology and clinical significance.
- Recognizing these specific histological findings can aid in diagnosis.