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In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
Published on: February 20, 2020
Unusual presentations of Visceral leishmaniasis
Rajniti Prasad1, Sunil Muthusami, Nisha Pandey
1Department of Pediatrics,Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India. rajnitip@gmail.com
Abstract:
We report 3 cases of Visceral leishmaniasis, who presented with unusual clinical manifestations. One child was diagnosed as hemophagocytic syndrome; another masqueraded with features of leukemoid changes alongwith hemophagocytosis and trilineage myelodysplasia; the third case presented with pyothorax. All the three patients showed amastigote forms of Leishmania donovani and positive serology (rk39 antigen). They showed complete clinical, hematological and parasitological resolution with Amphotericin B therapy.
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