Using impedance cardiography to detect subclinical cardiovascular disease in women with multiple risk factors: a
1Dermed Diagnostics Inc, Wheaton, IL 60189, USA. ademarzo.dermed@att.net
Insights
Impedance cardiography (ICG) detected subclinical cardiovascular disease (CVD) in women over 40 with risk factors. Abnormal ICG results can help initiate early, personalized preventive treatments for CVD.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Early detection of cardiovascular disease (CVD) is crucial for timely intervention and preventing disease progression.
- Subclinical CVD in women over 40 with cardiovascular risk factors remains a significant public health concern.
- Identifying individuals with asymptomatic CVD is essential for initiating preventive strategies.
Purpose of the Study:
- To investigate the utility of impedance cardiography (ICG) waveform analysis with postural changes for detecting functional CVD.
- To assess the prevalence of subclinical CVD in women older than 40 years with multiple cardiovascular risk factors.
Main Methods:
- Utilized impedance cardiography (ICG) to analyze cardiac function and vascular load in women aged over 40.
- Compared ICG data between a study group (n=32) with CVD risk factors and a control group (n=20) of healthy women.
- Assessed ICG parameters in both standing and supine positions to evaluate functional cardiovascular changes.
Main Results:
- All women in the study group exhibited abnormal ICG data, with 87.5% showing multiple abnormalities.
- ICG indicated ventricular dysfunction in 40.6%, high vascular resistive load in 43.8%, and elevated vascular pulsatile load in 93.8% of the study group.
- The control group consistently presented normal ICG findings.
Conclusions:
- Subclinical CVD is highly prevalent in women over 40 with multiple cardiovascular risk factors, as detected by ICG.
- Abnormal ICG findings suggest potential functional cardiovascular abnormalities that warrant further investigation.
- ICG shows promise as a non-invasive tool for early detection and personalized preventive treatment of CVD.
Abstract:
Early detection of cardiovascular disease (CVD) could initiate appropriate treatment and prevent progression. This study used impedance cardiography (ICG) waveform analysis with postural change to detect functional CVD in women older than 40 years with no history of CVD and >or=2 of the following risk factors: cigarette smoking, poor diet, physical inactivity, central adiposity, family history of premature CVD, hypertension, and dyslipidemia. A study group of 32 women underwent ICG in standing and supine positions. An age-matched control group had 20 women with an active lifestyle, no risk factors, and no history of CVD. All women in the control group had normal ICG data. All women in the study group had some abnormal ICG data, with 28 (87.5%) having multiple ICG abnormalities. ICG data indicated that 13 (40.6%) had ventricular dysfunction, 14 (43.8%) had high vascular resistive load, and 30 (93.8%) had elevated vascular pulsatile load. The data suggest that subclinical CVD, detectable by ICG, is prevalent in women older than 40 years with multiple risk factors. Abnormal ICG results could expedite the initiation of customized treatment as part of a preventive approach to CVD.
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