Age changes in the neuromuscular system of rats

Data relating to the effects of aging on the neuromuscular system of rats have been reviewed and summarized. Age effects of muscle, nerve and neuromuscular junction are presented only in a descriptive, qualitative manner, primarily due to paucity of well controlled experimentation in this area. Certain morphological and biochemical changes taking place with aging of the neuromuscular system are discussed, but no conclusive hypotheses can be presented at this time explaining diminution of motor activity in old animals.