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The influence of eccentric scanning of optical coherence tomography on retinal nerve fiber layer analysis in normal
Chungkwon Yoo1, Il Hoon Suh, Yong Yeon Kim
1Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
Aim:
To investigate the influence of eccentric scanning on retinal nerve fiber layer (RNFL) analysis using Stratus optical coherence tomography (OCT) in normal Koreans when the eccentricity of scanning occurs in 4 different directions.
Methods:
Thirty-one eyes of 31 persons underwent 1 concentric disk-centered and 4 superiorly, inferiorly, nasally and temporally eccentric RNFL OCT scans.
Results:
The average RNFL thickness measured by temporally eccentric scanning (115.1 microm) was significantly greater when compared with that found by concentric scanning (107.1 microm; p < 0.0001). The proportions of eyes outside normal limits on the RNFL analysis map using the criterion of >or=1 clock hour abnormal at the <1% level in superiorly (12/31, 38.7%), nasally (16/32, 51.6%) and temporally (12/31, 38.7%) eccentric scans were significantly different in comparison with the concentric (4/31, 12.9%) scan (p < 0.05).
Conclusion:
An off-centered OCT scan affected RNFL thickness measurement and its interpretation.
