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Updated: Jun 22, 2026

09:56
Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
Published on: August 31, 2021
Quantitative force mapping of an optical vortex trap
Abstract:
This paper describes the quantitative force mapping of micron-sized particles held in an optical vortex trap. We present a simple and efficient model, which accounts for the diffraction of the strongly localized optical field of the tightly focused laser beam, the spherical aberration introduced by the dielectric glass-to-water interface, employs the multidipole approximation for force calculations, and is able to reproduce, with quantitative agreement, the experimentally measured force map.

