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Updated: Jun 22, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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Variations in catechol-O-methyltransferase gene interact with parenting to influence attention in early development

P Voelker1, B E Sheese, M K Rothbart

  • 1Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA. pascale@uoregon.edu

Neuroscience
|June 2, 2009
PubMed
Summary

Genetic variations in the catechol-O-methyltransferase (COMT) gene impact attention in 2-year-olds, interacting with parenting quality. COMT haplotypes, not just single polymorphisms, better predict attention development.

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