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Updated: Jun 22, 2026

Isolation and Derivation of Mouse Embryonic Germinal Cells
Published on: October 22, 2009
Stem cell potential of the mammalian gonad
Chia-Feng Liu1, Ivraym Barsoum, Rupesh Gupta
1Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.
Abstract:
Stem cells have enormous potential for therapeutic application because of their ability to self-renew and differentiate into different cell types. Gonads, which consist of somatic cells and germ cells, are the only organs capable of transmitting genetic materials to the offspring. Germ-line stem cells and somatic stem cells have been found in the testis; however, the presence of stem cells in the ovary remains controversial. In this review, we discuss studies focusing on whether stem cell properties are present in the different cell types of male and female gonads and their implications on stem cell research.
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