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Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

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Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
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Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

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Male Sexual Response: Erection & Ejaculation

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Related Experiment Video

Updated: Jun 22, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Treatment of erectile dysfunction: update.

Rupesh Raina¹, Geetu Pahlajani, Ashok Agarwal

¹Centre for Advanced Human Reproduction Infertility and Sexual Function, Cleveland, OH, USA. rraina@metrohealth.org

American Journal of Men'S Health

|June 2, 2009

Summary

Erectile dysfunction (ED) is the inability to achieve and maintain an erection. New oral agents offer effective treatment options for ED, expanding beyond older methods like injections and devices.

Related Experiment Videos

Last Updated: Jun 22, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

Urology
Andrology
Pharmacology

Background:

Erectile dysfunction (ED) involves complex neural and vascular interactions.
Nitric oxide is a key neurotransmitter in achieving erections.
ED impacts men's health and quality of life.

Purpose of the Study:

To review the clinical management of erectile dysfunction.
To discuss advancements in ED treatment options.
To address ED specifically in the context of prostatectomy patients.

Main Methods:

Literature review of ED pathophysiology and treatments.
Analysis of current pharmacological interventions for ED.
Discussion of historical and emerging ED therapies.

Main Results:

Erectile function relies on intricate neural and vascular signaling.
Nitric oxide plays a crucial role in penile erection.
Oral agents represent a significant advancement in ED treatment.

Conclusions:

Modern ED management includes effective oral therapies.
Understanding ED mechanisms is vital for successful treatment.
Prostatectomy outcomes may be influenced by ED management strategies.