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Related Experiment Video

Updated: Jun 22, 2026

Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors

Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors

Published on: November 22, 2016

Electrochemical detection for paper-based microfluidics.

Wijitar Dungchai¹, Orawon Chailapakul, Charles S Henry

¹Sensor Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok, 10330, Thailand.

Analytical Chemistry

|June 3, 2009

Summary

This summary is machine-generated.

This study introduces the first electrochemical detection for paper-based microfluidic devices. These inexpensive, portable devices accurately measure glucose, lactate, and uric acid in biological samples for point-of-care monitoring.

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Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

Area of Science:

Analytical Chemistry
Biomedical Engineering
Materials Science

Background:

Paper-based microfluidic devices offer a low-cost, portable platform for diagnostics.
Electrochemical detection provides sensitive and selective analyte quantification.
Integrating these technologies enables accessible point-of-care testing.

Purpose of the Study:

To demonstrate the first electrochemical detection system for paper-based microfluidic devices.
To develop a method for simultaneous detection of multiple analytes using a single electrode type.
To validate the device's performance in analyzing biological samples.

Main Methods:

Microfluidic channels fabricated on filter paper using photolithography.
Screen-printed electrodes fabricated on paper-based microfluidic devices.
Cyclic voltammetry for electrode characterization and chronoamperometry for analyte detection.
Prussian Blue used as a redox mediator to enhance selectivity for hydrogen peroxide.

Main Results:

Successful characterization of screen-printed electrodes on paper using cyclic voltammetry.
Demonstrated utility for determining glucose, lactate, and uric acid in control serum samples.
Analyte levels measured by the paper devices were in agreement with traditional testing methods.
Achieved accurate quantification of glucose and lactate in two levels of control serum samples.

Conclusions:

Successful integration of paper-based microfluidics and electrochemical detection.
Developed an easy-to-use, inexpensive, and portable platform for point-of-care monitoring.
The system shows promise for widespread application in clinical diagnostics.