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The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

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Published on: July 4, 2013

Research ethics issues in geriatric psychiatry.

Laura B Dunn¹, Sahana Misra

¹Department of Psychiatry, University of California, San Francisco, 401 Parnassus Avenue, Box GPP-0984, San Francisco, CA 94143-0984, USA. laura.dunn@ucsf.edu

The Psychiatric Clinics of North America

|June 3, 2009

Summary

Ethical challenges in geriatric psychiatric research hinder progress. Addressing issues like proxy consent and advanced directives is crucial for protecting participants and ensuring research integrity.

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Area of Science:

Geriatric Psychiatry
Bioethics
Clinical Research

Background:

Ethical considerations are often overlooked in geriatric psychiatric research, potentially leading to negative consequences such as research bans or biased risk-benefit assessments by review boards.
Challenges in proxy consent and the use of advanced directives require further investigation to ensure ethical research conduct.

Purpose of the Study:

To identify and address ethical challenges in geriatric psychiatric research.
To explore issues surrounding proxy consent for cognitively impaired individuals.
To examine the utility of advanced directives in research involving individuals with impaired decision-making capacity.

Main Methods:

Review of state laws concerning research with cognitively impaired individuals.
Analysis of Institutional Review Board (IRB) practices in evaluating proxy consent.
Stakeholder surveys on perceptions of proxy consent.
Exploration of advanced directives' role in future consent.

Main Results:

Current state laws inadequately address research involving cognitively impaired individuals.
IRB practices for risk-benefit analysis in proxy consent require standardization.
Stakeholder views on proxy consent vary, highlighting the need for further research.
Advanced directives present challenges for specific study consent but may inform surrogate decision-making.

Conclusions:

Proactive identification and remediation of ethical issues are essential for advancing geriatric psychiatric research.
Further research is needed to develop standardized ethical procedures, particularly for depression and suicide studies involving proxy consent and advanced directives.