Related Experiment Video
Updated: Jun 22, 2026
09:31
Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
[Evaluation of cardiac function after neonatal asphyxia by Doppler tissue imaging]
1Department of Pediatrics, Jinhua Municipal Central Hospital, Jinhua 321000, China.
Zhonghua Yi Xue Za Zhi
|June 4, 2009
Summary
Neonatal asphyxia impairs both systolic and diastolic cardiac function. Doppler tissue imaging (DTI) detects these cardiac function changes more sensitively than M-mode ultrasound.
Area of Science:
- Neonatal cardiology
- Echocardiography
- Cardiovascular physiology
Background:
- Neonatal asphyxia is a critical condition affecting newborns.
- Cardiac dysfunction is a significant complication of neonatal asphyxia.
- Early and accurate assessment of cardiac function is crucial for management.
Purpose of the Study:
- To evaluate the effectiveness of Doppler tissue imaging (DTI) in assessing cardiac function changes post-neonatal asphyxia.
- To compare DTI findings with conventional echocardiographic parameters.
Main Methods:
- Sixty-two neonates with asphyxia were grouped into severe (Apgar ≤3) and mild (Apgar >3 and ≤7) categories.
- Thirty normal neonates served as controls.
- Doppler tissue imaging (DTI) measured myocardial velocities (DTIs, TDIe, DTIa, DTI e/a) at 24, 48, and 72 hours post-birth, compared with M-mode LVEF and pulsed Doppler E, A, E/A.
Main Results:
- Severe asphyxia group showed significantly lower LVEF and DTIs compared to controls.
- In severe asphyxia, DTIs values increased from 24 to 72 hours but remained lower than controls.
- Mild asphyxia group exhibited altered E, A, and E/A ratios, alongside reduced DTIe, DTIe/a, and elevated DTIa compared to controls.
Conclusions:
- Neonatal asphyxia leads to decreased left ventricular systolic and diastolic function.
- Doppler tissue imaging (DTI) provides more sensitive detection of cardiac function alterations than M-mode ultrasound in neonates with asphyxia.
