Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuing Care01:25

Continuing Care

Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Patient-centered Care01:13

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ROHHAD syndrome: an interdisciplinary perspective.

Frontiers in pediatrics·2026
Same author

<i>Letter:</i> Rethinking Pediatric Palliative Care and Organ Donation: From Critical Questions to New Opportunities.

Journal of palliative medicine·2026
Same author

DNA hydroxymethylation of NCX1 heart promoter by GATA6/TET3 epigenetic complex participates in neuroprotection induced by hypoxic preconditioning.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Extracting structured clinical data from pediatric emergency records using LLMs: A multimodel retrospective study of children with medical complexity.

Digital health·2026
Same author

Measuring the psychological symptoms of pediatric palliative care patients and their caregivers: a scoping review of available instruments.

BMC psychology·2026
Same author

Understanding Maternal Role in Caring for Children with Severe Cognitive Impairment in Paediatric Palliative Care: A Qualitative Pilot Study.

Children (Basel, Switzerland)·2026
Same journal

Incidence, mortality, and survival trends of retinoblastoma in children: a systematic review and meta-analysis of population-based studies.

Italian journal of pediatrics·2026
Same journal

Epidemiological trends of multidrug-resistant organisms in a tertiary-care pediatric hospital, 2017-2023.

Italian journal of pediatrics·2026
Same journal

Practice and challenges of newborn hearing screening: analysis of a five-year database in Italy.

Italian journal of pediatrics·2026
Same journal

Clinical characteristics in antibody-positive pediatric patients with immune-mediated necrotizing myopathy.

Italian journal of pediatrics·2026
Same journal

A comparison of pediatric sepsis definitions based on systemic inflammatory response syndrome and Phoenix criteria: a single-center PICU retrospective study.

Italian journal of pediatrics·2026
Same journal

A comparison between early onset sepsis (EOS) risk calculator and modified new protocol in a newborn ≥ 35 weeks: a simulation study.

Italian journal of pediatrics·2026
See all related articles

Related Experiment Videos

Pediatric palliative care.

Franca Benini1, Marco Spizzichino, Manuela Trapanotto

  • 1Department of Pediatrics, University of Padua, Padua, Italy. benini@pediatria.unipd.it.

Italian Journal of Pediatrics
|June 4, 2009
PubMed
Summary
This summary is machine-generated.

Pediatric palliative care improves quality of life for children with serious illnesses and their families. Despite challenges, home-based care is preferred, highlighting the need for better communication and support services.

Related Experiment Videos

Area of Science:

  • Palliative Care
  • Pediatric Oncology
  • Family Support

Background:

  • The World Health Organization defines pediatric palliative care as comprehensive care for the child's physical, mental, and spiritual well-being, including family support.
  • Severe, irreversible diseases impact pediatric patients, presenting complex clinical, psychological, ethical, and spiritual challenges.

Discussion:

  • Home is often the ideal setting for pediatric palliative care, yet cultural, educational, and organizational barriers limit its implementation.
  • International data show incurable diseases affect 10/10,000 young people annually, with a mortality rate of 1/10,000.
  • Patient needs consistently emphasize a desire for home-based care, improved professional communication, and enhanced support services.

Key Insights:

  • Despite diverse settings, the needs of pediatric patients with incurable diseases are remarkably similar worldwide.
  • Various care models, including institutional (hospice) and home-based (hospitalization, integrated programs), have been explored.
  • Effective pediatric palliative care requires specialized expertise, training, research, and robust organizational structures.

Outlook:

  • Addressing the underestimated needs of pediatric palliative care is crucial.
  • Further research and development of integrated home-based care models are essential.
  • Strengthening professional training and support systems will improve care delivery.