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Updated: Jun 22, 2026

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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
Obesity genes-it's all about the parents!
1University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. isf20@cam.ac.uk
Cell Metabolism
|June 4, 2009
Summary
Maternal GNAS1 gene mutations are linked to obesity. Researchers studied mice with specific gene deletions to understand how this genetic link to obesity develops.
Area of Science:
- Genetics
- Neuroscience
- Endocrinology
Background:
- Mutations in the GNAS1 gene, when maternally inherited, are associated with human obesity.
- The precise biological mechanism linking GNAS1 mutations to obesity remains unclear.
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