Related Experiment Video
Updated: Jun 22, 2026
08:23
A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
An electrode addressing protocol for imaging brain function with electrical impedance tomography using a 16-channel
1Department of Medical Physics and Bioengineering, Malet Place Engineering Building, Gower Street, University College London, London WC1E 6BT, UK. l.fabrizi@ucl.ac.uk
Physiological Measurement
|June 4, 2009
Summary
A new electrode protocol for electrical impedance tomography (EIT) of brain function significantly improved image quality. This advancement allows for better localization of abnormalities using 16 scalp electrodes.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Medical Imaging
Background:
- Electrical impedance tomography (EIT) faces challenges in brain imaging due to current diversion by the skull.
- Previous EIT protocols used widely spaced electrodes and multiplexers to maximize image resolution.
Purpose of the Study:
- To develop and test a novel electrode protocol for a 16-channel semi-parallel EIT system (KHU Mk1).
- To evaluate image reconstruction quality using simulated head models and realistic noise.
Main Methods:
- Ten electrode protocols were tested, employing spiral, spiral with suboccipital (spiral s-o), and zig-zag configurations.
- Current injection was applied using electrode pairs at 180, 120, and 60 degrees.
- Image quality was assessed based on localization error, resolution, distortion, and sensitivity.
Main Results:
- The spiral s-o configuration with combined current injection (180 + 120 + 60 degrees) yielded the best image quality.
- This protocol achieved reconstruction with a localization error under 10% of head diameter.
Conclusions:
- The developed electrode protocol enhances EIT imaging of brain function.
- Satisfactory imaging of focal brain abnormalities may be achievable with 16 scalp electrodes and improved instrumentation.
