Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parallel Activation and Interference CRISPR (PAIR) with Sequencing Uncovers DNA Repair Networks Guiding Precision Cell Engineering.

bioRxiv : the preprint server for biology·2026
Same author

Redefining Dendritic Cell Vaccines: Synergistically Co-priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Foundations of prosopagnosia: The three classic Austro-German reports.

Cortex; a journal devoted to the study of the nervous system and behavior·2025
Same author

Scanning faces: a deep learning approach to studying eye movements in prosopagnosia.

Frontiers in neurology·2025
Same author

Eye-hand coordination during a precision grasping and placement task in children with a history of amblyopia.

Vision research·2025
Same author

Development of the CRISPR/Cas9 system for genome editing in Riemerella anatipestifer.

Poultry science·2025

Related Experiment Video

Updated: Jun 22, 2026

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
10:05

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

Combined functional MRI and diffusion tensor imaging analysis of visual motion pathways.

Linda J Lanyon1, Deborah Giaschi, Simon Au Young

  • 1Human Vision and Eye Movement Laboratory, University of British Columbia, Vancouver, British Columbia, Canada. llanyon@eyecarecentre.org

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|June 4, 2009
PubMed
Summary

Direct brain connections bypassing the primary visual cortex (V1) may preserve motion perception. This study found evidence of these pathways in humans, potentially explaining vision without V1.

More Related Videos

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
13:26

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

Related Experiment Videos

Last Updated: Jun 22, 2026

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
10:05

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
13:26

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

Area of Science:

  • Neuroscience
  • Visual Perception
  • Neuroimaging

Background:

  • Motion perception can remain intact despite damage to the primary visual cortex (V1).
  • This suggests alternative pathways to motion-sensitive areas like V5/MT+ may exist.
  • Previous evidence in monkeys hinted at direct thalamic or collicular inputs bypassing V1.

Purpose of the Study:

  • To investigate direct neural connections between V5/MT+ and subcortical structures (thalamus/superior colliculus) in humans.
  • To explore potential pathways for motion processing independent of V1.

Main Methods:

  • Diffusion tensor imaging (DTI) tractography was used to map white matter tracts in 10 healthy volunteers.
  • V5/MT+ was localized using functional MRI (fMRI).
  • Tractography analysis focused on fibers connecting V5/MT+ to the posterior thalamus and/or superior colliculus, excluding V1 connections.

Main Results:

  • Direct white matter connections between the V5/MT+ region and the posterior thalamus and/or superior colliculus were identified in 4 out of 10 subjects.
  • These findings were obtained using conservative tractography parameters.

Conclusions:

  • The identified connections provide a potential neural basis for visual motion awareness in individuals with V1 damage.
  • These subcortical-cortical pathways may play a crucial role in preserving motion perception when V1 is non-functional.