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Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer Prevention

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Related Experiment Video

Updated: Jun 22, 2026

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

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Anticancer effects of phytosterols.

T A Woyengo¹, V R Ramprasath, P J H Jones

¹Department of Animal Sciences, University of Manitoba, Winnipeg, Manitoba R3T6C5, Canada.

European Journal of Clinical Nutrition

|June 4, 2009

Summary

Phytosterols, plant compounds that lower LDL cholesterol, show promise in preventing various cancers. Safe at recommended doses, they offer dual benefits for heart health and cancer risk reduction.

Area of Science:

Nutritional Science
Oncology
Biochemistry

Background:

Phytosterols and stanols reduce cholesterol absorption, lowering cardiovascular disease risk.
Emerging research suggests additional biological roles for phytosterols beyond cholesterol management.

Purpose of the Study:

To critically review recent research on the potential anti-cancer effects and mechanisms of phytosterols.
To evaluate the evidence for phytosterol's role in cancer prevention.

Main Methods:

Literature review of recent scientific studies.
Analysis of proposed mechanisms of action for phytosterols in cancer.
Examination of safety data for phytosterol consumption.

Main Results:

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Phytosterols demonstrate inhibitory effects against lung, stomach, ovarian, and breast cancers.
Mechanisms include inhibiting carcinogen production, cancer cell growth, angiogenesis, invasion, metastasis, and promoting apoptosis.
Phytosterols may enhance antioxidant enzyme activity and reduce oxidative stress.
Consumption at 2 g/day is considered safe for healthy individuals.

Conclusions:

Growing evidence supports phytosterols' role in cancer prevention.
Phytosterols offer a dual benefit for reducing cardiovascular disease risk and potentially preventing cancer.
Dietary incorporation of phytosterols is recommended for both cardiovascular and cancer protective effects.