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Updated: Jun 22, 2026
08:06
The Immediate Partial Removal of Cumulus-Oocyte Complexes: A Refined Approach for Rapid Observation of In Vitro Fertilization
Published on: October 18, 2024
Fertilization in vitro.
Yinzhong Bing1, Rodney J Ouellette
1Conceptia Clinic, Hôtel Dieu Pavilion, Dr Georges L Dumont Hospital, Atlantic Cancer Research Institute, Moncton, New-Brunswick, Canada.
Methods in Molecular Biology (Clifton, N.J.)
|June 5, 2009
Summary
In vitro fertilization (IVF) enhances infertility treatment through advanced lab techniques. This review details methods to maximize IVF success rates for accessible, effective care.
Area of Science:
- Reproductive medicine andrology
- Embryology and gamete biology
Background:
- In vitro fertilization (IVF) has been a cornerstone of infertility treatment since 1978.
- Significant advancements in laboratory procedures have continuously improved IVF success rates.
Purpose of the Study:
- To review established and novel laboratory procedures in IVF.
- To provide insights into maximizing IVF success rates through efficient techniques and technology.
Main Methods:
- Review of key IVF laboratory techniques including sperm treatment, intracytoplasmic sperm injection (ICSI), embryo culture, cryopreservation, and pre-implantation genetic diagnosis (PGD).
Main Results:
- The evolution of IVF laboratory procedures has led to steadily increasing success rates.
- Specific techniques like ICSI and PGD have significantly contributed to improved outcomes.
Conclusions:
- Optimizing laboratory procedures is crucial for enhancing the effectiveness and accessibility of IVF.
- Continued technological evolution promises to further refine IVF as a safe and effective infertility treatment.
Related Concept Videos
01:24In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
01:38Fertilization
During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
01:16In-vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
01:57Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...