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Difficulties or mistakes in diagnosing type 1 diabetes in children?--demographic factors influencing delayed
Małgorzata Pawłowicz1, Dorota Birkholz, Maciej Niedźwiecki
1The Department of Paediatrics, Hematology, Oncology and Endocrinology, Medical University in Gdańsk ul. Debinki 7 80-952 Gdańsk, Poland. malgorzatapawlowicz@amg.gda.pl
Insights
Delayed diagnosis of type 1 diabetes (T1DM) in children leads to diabetic ketoacidosis (DKA). Younger children, especially those under 2, face the highest risk of diagnostic delays, highlighting the need for increased pediatrician awareness.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Background:
- Diabetic ketoacidosis (DKA) is a severe complication of new-onset type 1 diabetes (T1DM) in children, often resulting from delayed diagnosis.
- Estimating the frequency of diagnostic difficulties and identifying demographic factors influencing these delays is crucial for timely T1DM management.
Purpose of the Study:
- To determine the incidence of diagnostic challenges in new-onset T1DM in children.
- To investigate the impact of demographic factors on the delay in diagnosing T1DM.
Main Methods:
- A retrospective analysis was conducted on 474 children under 17 with new-onset T1DM in the Pomeranian region of Poland.
- Diagnostic delay was defined as failure to diagnose T1DM on the initial visit due to various reasons including misinterpretation of symptoms or co-existing conditions.
Main Results:
- Diagnostic difficulties were identified in 14.13% of cases, significantly contributing to DKA development (p = 0.00).
- Patient's age at presentation was a key factor in diagnostic delays (p = 0.01), particularly for children under 2 years old (p = 0.00).
- Family doctors most often made incorrect preliminary diagnoses.
Conclusions:
- Diagnostic delays in pediatric T1DM are a major cause of DKA.
- Younger age, especially under 2 years, is the primary risk factor for delayed T1DM diagnosis.
- Enhanced awareness among pediatricians regarding T1DM in children is essential.
Background:
Diabetic ketoacidosis (DKA) development in children with new-onset type 1 diabetes (T1DM) is often the main consequence of delayed diagnosis. The aim of the study was to estimate the frequency of difficulties in T1DM diagnosis and to investigate if and how the demographic factors (gender, patient's age at presentation, family history of T1DM, level of maternal education, place of residence, and health service unit the patient called at) have any influence on diagnostic delays.
Subjects And Methods:
Retrospective analysis of 474 children (243 boys-51.27% and 231 girls -48.73%) with new-onset T1DM aged below 17 yr and living in the Pomeranian region of Poland was carried out. The delay in diagnosis was recognized if the patient was not diagnosed on the first visit because of omission, wrong interpretation of main diabetic symptoms, exclusive treatment of additional signs, or concomitant diseases.
Results:
Difficulties in diagnosing T1DM were found in 67 cases (14.13%) and they are the main cause of DKA development in these children (p = 0.00). Among the examined demographic factors, mainly the patient's age at presentation has a significant influence on diagnostic delays (p = 0.01), especially in children below 2 yr (p = 0.00). Most frequently family doctors were responsible for wrong preliminary diagnosis.
Conclusions:
Difficulties in diagnosing T1DM are a significant cause of DKA development in children with new-onset disease. Patient's age at presentation is the main risk factor of delayed diagnosis, especially in children below 2 yr. The increase in awareness among pediatricians concerning the possibility of T1DM development in children is needed.
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