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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Neuroimaging of cognitive impairments in vascular disease

Carol Di Perri1, Turi O Dalaker, Mona K Beyer

  • 1Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo, Buffalo, New York 14203, USA.

International Review of Neurobiology
|June 9, 2009
PubMed

Insights

Cerebrovascular disease (CVD) is a major cause of cognitive impairment and dementia. Vascular cognitive impairment (VCI) encompasses cognitive changes linked to vascular issues, often affecting executive function.

Area of Science:

  • Neurology
  • Neuroscience
  • Geriatrics

Background:

  • Cerebrovascular disease (CVD) is a significant contributor to cognitive decline and dementia.
  • CVD often co-occurs with neurodegenerative diseases like Alzheimer's disease.
  • Vascular pathology underlies a spectrum of cognitive deficits.

Purpose of the Study:

  • To introduce and define vascular cognitive impairment (VCI) as a diagnostic concept.
  • To highlight the association between vascular pathology and cognitive changes.
  • To describe the characteristic features of VCI.

Main Methods:

  • Literature review and synthesis of existing research on CVD and cognition.
  • Conceptual framework development for VCI.
  • Clinical feature analysis of cognitive changes related to vascular pathology.

Main Results:

  • CVD is a primary driver of cognitive impairment and dementia.
  • Vascular cognitive impairment (VCI) represents a broad range of cognitive deficits.
  • Executive dysfunction is a key feature of VCI, often accompanied by noncognitive symptoms.

Conclusions:

  • Vascular cognitive impairment (VCI) is a critical concept for understanding cognitive decline in CVD.
  • Recognizing VCI is essential for accurate diagnosis and management.
  • Further research is needed to fully elucidate the spectrum and impact of VCI.

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