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17q21.31 microduplication patients are characterised by behavioural problems and poor social interaction

B Grisart1, L Willatt, A Destrée

  • 1Centre de Génétique Humaine, Institut de Pathologie et de Génétique, B-6041 Charleroi, Belgium. bernard.grisart@ipg.be

Journal of Medical Genetics
|June 9, 2009
PubMed
Summary

The 17q21.31 duplication syndrome, identified in four patients, presents with intellectual skills ranging from normal to mild mental retardation and autistic features. This genetic condition arises from maternal origin and highlights the role of genomic architecture in its development.

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