Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Altering ventilator inspiratory time can reduce autocycling during sleep.

Sleep medicine·2015
Same author

On the nature of consciousness and of physical reality.

Perspectives in biology and medicine·2015
Same author

Optical pacing of the adult rabbit heart.

Biomedical optics express·2013
Same author

Anti-resorptive agents reduce the size of resorption cavities: a three-dimensional dynamic bone histomorphometry study.

Bone·2013
Same author

Altering embryonic cardiac dynamics with optical pacing.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2013
Same author

Obstructive sleep apnea and pregnancy: the effect on perinatal outcomes.

Journal of perinatology : official journal of the California Perinatal Association·2012

Related Experiment Video

Updated: Jun 22, 2026

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
12:54

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo

Published on: October 2, 2021

4D embryonic cardiography using gated optical coherence tomography.

M W Jenkins, F Rothenberg, D Roy

    Optics Express
    |June 9, 2009
    PubMed
    Summary
    This summary is machine-generated.

    We developed a new gated optical coherence tomography (OCT) technique for high-resolution, four-dimensional (4D) imaging of early embryonic heart development and function. This method overcomes previous limitations, enabling detailed study of cardiac physiology and congenital heart defects.

    More Related Videos

    Murine Fetal Echocardiography
    08:04

    Murine Fetal Echocardiography

    Published on: February 15, 2013

    Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)
    10:13

    Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)

    Published on: December 12, 2016

    Related Experiment Videos

    Last Updated: Jun 22, 2026

    Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
    12:54

    Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo

    Published on: October 2, 2021

    Murine Fetal Echocardiography
    08:04

    Murine Fetal Echocardiography

    Published on: February 15, 2013

    Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)
    10:13

    Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)

    Published on: December 12, 2016

    Area of Science:

    • Cardiovascular Research
    • Developmental Biology
    • Biomedical Imaging

    Background:

    • Simultaneous imaging of early embryonic heart structure and function faces spatial and temporal resolution limitations.
    • Existing techniques struggle to provide the necessary detail for studying embryonic cardiac development.
    • Understanding early heart development is crucial for identifying causes of congenital heart defects.

    Purpose of the Study:

    • To develop and validate a novel gated optical coherence tomography (OCT) technique for high-resolution, four-dimensional (4D) imaging of embryonic hearts.
    • To overcome the technical limitations of spatial and temporal resolution in current embryonic cardiac imaging.
    • To enable longitudinal investigation of intact embryonic heart physiology and the events leading to congenital heart defects.

    Main Methods:

    • Developed a gated sampling technique using optical coherence tomography (OCT).
    • Acquired 4D imaging data from paced, excised embryonic chicken and mouse hearts.
    • Employed advanced image processing to visualize cardiac structures and measure physiological parameters.

    Main Results:

    • Achieved high spatial resolution (10-15 mum) and sufficient depth penetration (1.5-2.0 mm) for early embryonic hearts.
    • Successfully visualized beating embryonic hearts in 4D, enabling measurement of cardiac volume, ejection fraction, and wall thickness.
    • Demonstrated the feasibility of the technique for studying embryonic cardiac function and structure.

    Conclusions:

    • The developed gated OCT technique provides unprecedented 4D imaging capabilities for embryonic hearts.
    • This technique overcomes previous resolution limitations, offering a powerful tool for developmental cardiology research.
    • It holds significant potential for longitudinally investigating embryonic heart physiology and congenital heart defect origins.