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A highly selective and sensitive fluorescent turn-on sensor for Hg2+ and its application in live cell imaging
Hua Lu1, Liqin Xiong, Hanzhuang Liu
1State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, 210093, PR China.
Organic & Biomolecular Chemistry
|June 9, 2009
Abstract:
A boron-dipyrromethene (BODIPY) derivative containing a tridentate diaza-oxa ligand (8H-BDP) was synthesized as a fluorescent turn-on chemosensor for Hg(2+) with high sensitivity (detection limit < or = 2 ppb), a rapid response time (< or = 5 seconds) and specific selectivity over other cations under physiological conditions and in live cells according to the confocal fluorescence microscopy experiment.
