Related Experiment Video
Updated: Jun 22, 2026

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
Published on: May 12, 2023
Supportive care: managing febrile neutropenia
1Paediatric Oncology Unit, Birmingham Children's Hospital NHS Foundation Trust.
Abstract:
Chemotherapy, the most commonly used treatment for childhood cancer, can have a devastating effect on the immune system, reducing defences against infection, particularly bacterial infection, a common cause of life-threatening sepsis. Before they leave hospital for the first time after diagnosis, patients and carers need to understand what neutropenia is and how to monitor for and recognise signs and symptoms of infection. This article describes the approach to the nursing aspects of managing febrile neutropenia at Birmingham Children's Hospital NHS Foundation Trust. Approaches to avoiding infection at home include good hand hygiene and careful management of food, drink and the child's environment. There needs to be a balance between avoiding infection risks and allowing the child to maintain a normal social life, including attending school. Preventing infection in hospital requires similar measures to those required to prevent infection in any patient. Careful monitoring of the neutropenic child is necessary so that infection is recognised early and treatment initiated rapidly. National, evidence-based guidelines for the prevention and management of febrile neutropenia should be followed, particularly the open access policy enabling patients/carers to call for advice 24 hours a day.
Related Concept Videos
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Urinary Tract Infection IV: Nursing Management
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Nephrotic Syndrome III : Nursing Management
Acute Kidney Injury VI: Nursing Management
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include: